Collage of published research papers

Citation

BibTex format

@article{Miao:2024:10.1038/s41593-024-01638-y,
author = {Miao, A and Luo, T and Hsieh, B and Edge, CJ and Gridley, M and Wong, R and Constandinou, T and Wisden, W and Franks, N},
doi = {10.1038/s41593-024-01638-y},
journal = {Nature Neuroscience},
pages = {1046--1050},
title = {Brain clearance is reduced during sleep and anesthesia},
url = {http://dx.doi.org/10.1038/s41593-024-01638-y},
volume = {27},
year = {2024}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - It has been suggested that the function of sleep is to actively clear metabolites and toxins from the brain. Enhanced clearance is also said to occur during anesthesia. Here, we measure clearance and movement of fluorescent molecules in the brains of male mice and show that movement is, in fact, independent of sleep and wake or anesthesia. Moreover, we show that brain clearance is markedly reduced, not increased, during sleep and anesthesia.
AU  - Miao,A
AU  - Luo,T
AU  - Hsieh,B
AU  - Edge,CJ
AU  - Gridley,M
AU  - Wong,R
AU  - Constandinou,T
AU  - Wisden,W
AU  - Franks,N
DO  - 10.1038/s41593-024-01638-y
EP  - 1050
PY  - 2024///
SN  - 1097-6256
SP  - 1046
TI  - Brain clearance is reduced during sleep and anesthesia
T2  - Nature Neuroscience
UR  - http://dx.doi.org/10.1038/s41593-024-01638-y
UR  - https://www.nature.com/articles/s41593-024-01638-y
UR  - http://hdl.handle.net/10044/1/110528
VL  - 27
ER  -
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Awards

  • Finalist: Best Paper - IEEE Transactions on Mechatronics (awarded June 2021)

  • Finalist: IEEE Transactions on Mechatronics; 1 of 5 finalists for Best Paper in Journal

  • Winner: UK Institute of Mechanical Engineers (IMECHE) Healthcare Technologies Early Career Award (awarded June 2021): Awarded to Maria Lima (UKDRI CR&T PhD candidate)

  • Winner: Sony Start-up Acceleration Program (awarded May 2021): Spinout company Serg Tech awarded (1 of 4 companies in all of Europe) a place in Sony corporation start-up boot camp

  • “An Extended Complementary Filter for Full-Body MARG Orientation Estimation” (CR&T authors: S Wilson, R Vaidyanathan)

UK DRI

Established in 2017 by its principal funder the Medical Research Council, in partnership with Alzheimer's Society and Alzheimer’s Research UK, The UK Dementia Research Institute (UK DRI) is the UK’s leading biomedical research institute dedicated to neurodegenerative diseases.

Funding provided by the

Medical Research Council

Funding provided by the

Alzheimer's Society

Funding provided by

Alzheimer's Research UK