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Synthetic Biology underpins advances in the bioeconomy

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology. 

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Hazel:2018:10.1002/cmdc.201700826,
author = {Hazel, P and Kroll, SHB and Bondke, A and Barbazanges, M and Patel, H and Fuchter, MJ and Coombes, RC and Ali, S and Barrett, AGM and Freemont, PS},
doi = {10.1002/cmdc.201700826},
journal = {ChemMedChem},
pages = {207--207},
title = {Corrigendum: Inhibitor selectivity for cyclin-dependent kinase7: a structural, thermodynamic, and modelling study},
url = {http://dx.doi.org/10.1002/cmdc.201700826},
volume = {13},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AU - Hazel,P
AU - Kroll,SHB
AU - Bondke,A
AU - Barbazanges,M
AU - Patel,H
AU - Fuchter,MJ
AU - Coombes,RC
AU - Ali,S
AU - Barrett,AGM
AU - Freemont,PS
DO - 10.1002/cmdc.201700826
EP - 207
PY - 2018///
SN - 1860-7187
SP - 207
TI - Corrigendum: Inhibitor selectivity for cyclin-dependent kinase7: a structural, thermodynamic, and modelling study
T2 - ChemMedChem
UR - http://dx.doi.org/10.1002/cmdc.201700826
UR - http://hdl.handle.net/10044/1/60677
VL - 13
ER -

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Work in the IC-CSynB is supported by a wide range of Research Councils, Learned Societies, Charities and more.