In this section

Research

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology.

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Chambers:2016:10.1042/BST20160007,
author = {Chambers, S and Kitney, R and Freemont, P},
doi = {10.1042/BST20160007},
journal = {Biochemical Society Transactions},
pages = {687--688},
title = {The Foundry: the DNA synthesis and construction Foundry at Imperial College.},
url = {http://dx.doi.org/10.1042/BST20160007},
volume = {44},
year = {2016}
}

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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The establishment of a DNA synthesis and construction foundry at Imperial College in London heralds a new chapter in the development of synthetic biology to meet new global challenges. The Foundry employs the latest technology to make the process of engineering biology easier, faster and scalable. The integration of advanced software, automation and analytics allows the rapid design, build and testing of engineered organisms.
AU  - Chambers,S
AU  - Kitney,R
AU  - Freemont,P
DO  - 10.1042/BST20160007
EP  - 688
PY  - 2016///
SN  - 1470-8752
SP  - 687
TI  - The Foundry: the DNA synthesis and construction Foundry at Imperial College.
T2  - Biochemical Society Transactions
UR  - http://dx.doi.org/10.1042/BST20160007
UR  - http://hdl.handle.net/10044/1/34186
VL  - 44
ER  -