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Research

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology.

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Beal:2020:10.15252/embr.202050521,
author = {Beal, J and Goñi-Moreno, A and Myers, C and Hecht, A and de, Vicente MDC and Parco, M and Schmidt, M and Timmis, K and Baldwin, G and Friedrichs, S and Freemont, P and Kiga, D and Ordozgoiti, E and Rennig, M and Rios, L and Tanner, K and de, Lorenzo V and Porcar, M},
doi = {10.15252/embr.202050521},
journal = {EMBO Reports},
pages = {1--5},
title = {The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?},
url = {http://dx.doi.org/10.15252/embr.202050521},
volume = {21},
year = {2020}
}

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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Synthetic biology needs to adopt sound scientific and industry-like standards in order to achieve its ambitious goals of efficient and accurate engineering of biological systems.
AU  - Beal,J
AU  - Goñi-Moreno,A
AU  - Myers,C
AU  - Hecht,A
AU  - de,Vicente MDC
AU  - Parco,M
AU  - Schmidt,M
AU  - Timmis,K
AU  - Baldwin,G
AU  - Friedrichs,S
AU  - Freemont,P
AU  - Kiga,D
AU  - Ordozgoiti,E
AU  - Rennig,M
AU  - Rios,L
AU  - Tanner,K
AU  - de,Lorenzo V
AU  - Porcar,M
DO  - 10.15252/embr.202050521
EP  - 5
PY  - 2020///
SN  - 1469-221X
SP  - 1
TI  - The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?
T2  - EMBO Reports
UR  - http://dx.doi.org/10.15252/embr.202050521
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32337821
UR  - https://www.embopress.org/doi/full/10.15252/embr.202050521
UR  - http://hdl.handle.net/10044/1/78984
VL  - 21
ER  -