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Research

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology.

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Evans:2020:10.1126/science.aba2932,
author = {Evans, SW and Beal, J and Berger, K and Bleijs, DA and Cagnetti, A and Ceroni, F and Epstein, GL and Garcia-Reyero, N and Gillum, DR and Harkess, G and Hillson, NJ and Hogervorst, PAM and Jordan, JL and Lacroix, G and Moritz, R and ÓhÉigeartaigh, SS and Palmer, MJ and van, Passel MWJ},
doi = {10.1126/science.aba2932},
journal = {Science},
pages = {138--140},
title = {Embrace experimentation in biosecurity governance},
url = {http://dx.doi.org/10.1126/science.aba2932},
volume = {368},
year = {2020}
}

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RIS format (EndNote, RefMan)

TY  - JOUR
AU  - Evans,SW
AU  - Beal,J
AU  - Berger,K
AU  - Bleijs,DA
AU  - Cagnetti,A
AU  - Ceroni,F
AU  - Epstein,GL
AU  - Garcia-Reyero,N
AU  - Gillum,DR
AU  - Harkess,G
AU  - Hillson,NJ
AU  - Hogervorst,PAM
AU  - Jordan,JL
AU  - Lacroix,G
AU  - Moritz,R
AU  - ÓhÉigeartaigh,SS
AU  - Palmer,MJ
AU  - van,Passel MWJ
DO  - 10.1126/science.aba2932
EP  - 140
PY  - 2020///
SN  - 0036-8075
SP  - 138
TI  - Embrace experimentation in biosecurity governance
T2  - Science
UR  - http://dx.doi.org/10.1126/science.aba2932
UR  - https://science.sciencemag.org/content/368/6487/138
UR  - http://hdl.handle.net/10044/1/79102
VL  - 368
ER  -