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Research

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology.

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Ellis:2019:10.1042/bio04103006,
author = {Ellis, T},
doi = {10.1042/bio04103006},
journal = {The Biochemist},
pages = {6--9},
title = {What is synthetic genomics anyway?},
url = {http://dx.doi.org/10.1042/bio04103006},
volume = {41},
year = {2019}
}

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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - You may have heard of synthetic genomics. This headline-grabbing, high-profile, big science topic is starting to emerge catalysed by the pioneering work of famous names in synthetic biology and biotechnology like George Church and Craig Venter. But what is synthetic genomics and what is it being used for? As a prominent researcher at a recent UK meeting said: “Is it just synthetic biology with bigger bits of DNA?” Well no, not quite…
AU  - Ellis,T
DO  - 10.1042/bio04103006
EP  - 9
PY  - 2019///
SN  - 0954-982X
SP  - 6
TI  - What is synthetic genomics anyway?
T2  - The Biochemist
UR  - http://dx.doi.org/10.1042/bio04103006
UR  - https://portlandpress.com/biochemist/article/41/3/6/284/What-is-synthetic-genomics-anyway
UR  - http://hdl.handle.net/10044/1/76275
VL  - 41
ER  -

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