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Research

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology.

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Lai:2019:10.1016/j.tibtech.2019.05.011,
author = {Lai, H-E and Canavan, C and Cameron, L and Moore, S and Danchenko, M and Kuiken, T and Sekeyová, Z and Freemont, PS},
doi = {10.1016/j.tibtech.2019.05.011},
journal = {Trends in Biotechnology},
pages = {1146--1151},
title = {Synthetic biology and the United Nations},
url = {http://dx.doi.org/10.1016/j.tibtech.2019.05.011},
volume = {37},
year = {2019}
}

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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Synthetic biology is a rapidly emerging interdisciplinary field of science and engineering that aims to redesign living systems through reprogramming genetic information. The field has catalysed global debate among policymakers and publics. Here we describe how synthetic biology relates to these international deliberations, particularly the Convention on Biological Diversity (CBD).
AU  - Lai,H-E
AU  - Canavan,C
AU  - Cameron,L
AU  - Moore,S
AU  - Danchenko,M
AU  - Kuiken,T
AU  - Sekeyová,Z
AU  - Freemont,PS
DO  - 10.1016/j.tibtech.2019.05.011
EP  - 1151
PY  - 2019///
SN  - 0167-7799
SP  - 1146
TI  - Synthetic biology and the United Nations
T2  - Trends in Biotechnology
UR  - http://dx.doi.org/10.1016/j.tibtech.2019.05.011
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31257057
UR  - https://www.sciencedirect.com/science/article/pii/S0167779919301337?via%3Dihub
UR  - http://hdl.handle.net/10044/1/71722
VL  - 37
ER  -