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Research

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology.

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Hillson:2019:10.1038/s41467-019-10079-2,
author = {Hillson, N and Caddick, M and Cai, Y and Carrasco, JA and Chang, MW and Curach, NC and Bell, DJ and Le, Feuvre R and Friedman, DC and Fu, X and Gold, ND and Herrgard, MJ and Holowko, MB and Johnson, JR and Johnson, RA and Keasling, JD and Kitney, RI and Kondo, A and Liu, C and Martin, VJJ and Menolascina, F and Ogino, C and Patron, NJ and Pavan, M and Poh, CL and Pretorius, IS and Rosser, SJ and Scrutton, NS and Storch, M and Tekotte, H and Travnik, E and Vickers, CE and Yew, WS and Yuan, Y and Zhao, H and Freemont, PS},
doi = {10.1038/s41467-019-10079-2},
journal = {NATURE COMMUNICATIONS},
pages = {1--4},
title = {Building a global alliance of biofoundries},
url = {http://dx.doi.org/10.1038/s41467-019-10079-2},
volume = {10},
year = {2019}
}

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RIS format (EndNote, RefMan)

TY  - JOUR
AU  - Hillson,N
AU  - Caddick,M
AU  - Cai,Y
AU  - Carrasco,JA
AU  - Chang,MW
AU  - Curach,NC
AU  - Bell,DJ
AU  - Le,Feuvre R
AU  - Friedman,DC
AU  - Fu,X
AU  - Gold,ND
AU  - Herrgard,MJ
AU  - Holowko,MB
AU  - Johnson,JR
AU  - Johnson,RA
AU  - Keasling,JD
AU  - Kitney,RI
AU  - Kondo,A
AU  - Liu,C
AU  - Martin,VJJ
AU  - Menolascina,F
AU  - Ogino,C
AU  - Patron,NJ
AU  - Pavan,M
AU  - Poh,CL
AU  - Pretorius,IS
AU  - Rosser,SJ
AU  - Scrutton,NS
AU  - Storch,M
AU  - Tekotte,H
AU  - Travnik,E
AU  - Vickers,CE
AU  - Yew,WS
AU  - Yuan,Y
AU  - Zhao,H
AU  - Freemont,PS
DO  - 10.1038/s41467-019-10079-2
EP  - 4
PY  - 2019///
SN  - 2041-1723
SP  - 1
TI  - Building a global alliance of biofoundries
T2  - NATURE COMMUNICATIONS
UR  - http://dx.doi.org/10.1038/s41467-019-10079-2
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000467534800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.nature.com/articles/s41467-019-10079-2
UR  - http://hdl.handle.net/10044/1/74012
VL  - 10
ER  -