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Research

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology.

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Gorochowski:2018:10.1038/nbt.4257,
author = {Gorochowski, TE and Ellis, T},
doi = {10.1038/nbt.4257},
journal = {NATURE BIOTECHNOLOGY},
pages = {934--935},
title = {Designing efficient translation},
url = {http://dx.doi.org/10.1038/nbt.4257},
volume = {36},
year = {2018}
}

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RIS format (EndNote, RefMan)

TY  - JOUR
AU  - Gorochowski,TE
AU  - Ellis,T
DO  - 10.1038/nbt.4257
EP  - 935
PY  - 2018///
SN  - 1087-0156
SP  - 934
TI  - Designing efficient translation
T2  - NATURE BIOTECHNOLOGY
UR  - http://dx.doi.org/10.1038/nbt.4257
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000447001600010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
VL  - 36
ER  -

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