In this section
@article{Caballero:2019:10.1007/s10856-018-6201-y,
author = {Caballero, SSR and Saiz, E and Montembault, A and Tadier, S and Maire, E and David, L and Delair, T and Gremillard, L},
doi = {10.1007/s10856-018-6201-y},
journal = {Journal of Materials Science: Materials in Medicine},
title = {3-D printing of chitosan-calcium phosphate inks: rheology, interactions and characterization},
url = {http://dx.doi.org/10.1007/s10856-018-6201-y},
volume = {30},
year = {2019}
}
TY - JOUR
AB - Bone substitute fabrication is of interest to meet the worldwide incidence of bone disorders. Physical chitosan hydrogels with intertwined apatite particles were chosen to meet the bio-physical and mechanical properties required by a potential bone substitute. A set up for 3-D printing by robocasting was found adequate to fabricate scaffolds. Inks consisted of suspensions of calcium phosphate particles in chitosan acidic aqueous solution. The inks are shear-thinning and consist of a suspension of dispersed platelet aggregates of dicalcium phosphate dihydrate in a continuous chitosan phase. The rheological properties of the inks were studied, including their shear-thinning characteristics and yield stress. Scaffolds were printed in basic water/ethanol baths to induce transformation of chitosan-calcium phosphates suspension into physical hydrogel of chitosan mineralized with apatite. Scaffolds consisted of a chitosan polymeric matrix intertwined with poorly crystalline apatite particles. Results indicate that ink rheological properties could be tuned by controlling ink composition: in particular, more printable inks are obtained with higher chitosan concentration (0.19 mol·L−1).
AU - Caballero,SSR
AU - Saiz,E
AU - Montembault,A
AU - Tadier,S
AU - Maire,E
AU - David,L
AU - Delair,T
AU - Gremillard,L
DO - 10.1007/s10856-018-6201-y
PY - 2019///
SN - 0957-4530
TI - 3-D printing of chitosan-calcium phosphate inks: rheology, interactions and characterization
T2 - Journal of Materials Science: Materials in Medicine
UR - http://dx.doi.org/10.1007/s10856-018-6201-y
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454541900004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/66378
VL - 30
ER -