Citation

BibTex format

@article{Wurtz:2018:1367-2630/aab549,
author = {Wurtz, J and Lee, C},
doi = {1367-2630/aab549},
journal = {New Journal of Physics},
pages = {1--20},
title = {Stress granule formation via ATP depletion-triggered phase separation},
url = {http://dx.doi.org/10.1088/1367-2630/aab549},
volume = {20},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Stress granules (SG) are droplets of proteins and RNA that formin the cell cytoplasm during stress conditions. We consider minimal models ofstress granule formation based on the mechanism of phase separation regulatedby ATP-driven chemical reactions. Motivated by experimental observations, weidentify a minimal model of SG formation triggered by ATP depletion. Ouranalysis indicates that ATP is continuously hydrolysed to deter SG formationunder normal conditions, and we provide specific predictions that can be testedexperimentally.
AU - Wurtz,J
AU - Lee,C
DO - 1367-2630/aab549
EP - 20
PY - 2018///
SN - 1367-2630
SP - 1
TI - Stress granule formation via ATP depletion-triggered phase separation
T2 - New Journal of Physics
UR - http://dx.doi.org/10.1088/1367-2630/aab549
UR - https://iopscience.iop.org/article/10.1088/1367-2630/aab549
UR - http://hdl.handle.net/10044/1/57849
VL - 20
ER -

Join the network

Join our mailing list for regular updates, news, events and opportunities