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@article{Yap:2017:10.1039/C7SM00818J,
author = {Yap, L and Endres, RG},
doi = {10.1039/C7SM00818J},
journal = {Soft Matter},
pages = {8089--8095},
title = {A model of cell-wall dynamics during sporulation in Bacillus subtilis},
url = {http://dx.doi.org/10.1039/C7SM00818J},
volume = {13},
year = {2017}
}
TY - JOUR
AB - To survive starvation, Bacillus subtilis forms durable spores. After asymmetric cell division, the septum grows around the forespore in a process called engulfment, but the mechanism of force generation is unknown. Here, we derived a novel biophysical model for the dynamics of cell-wall remodeling during engulfment based on a balancing of dissipative, active, and mechanical forces. By plotting phase diagrams, we predict that sporulation is promoted by a line tension from the attachment of the septum to the outer cell wall, as well as by an imbalance in turgor pressures in the mother-cell and forespore compartments. We also predict that significant mother-cell growth hinders engulfment. Hence, relatively simple physical principles may guide this complex biological process.
AU - Yap,L
AU - Endres,RG
DO - 10.1039/C7SM00818J
EP - 8095
PY - 2017///
SN - 1744-683X
SP - 8089
TI - A model of cell-wall dynamics during sporulation in Bacillus subtilis
T2 - Soft Matter
UR - http://dx.doi.org/10.1039/C7SM00818J
UR - http://hdl.handle.net/10044/1/51835
VL - 13
ER -
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