In this section
@article{Qureshi:2023:10.1063/5.0133489,
author = {Qureshi, BJ and Juritz, J and Poulton, JM and Beersing-Vasquez, A and Ouldridge, TE},
doi = {10.1063/5.0133489},
journal = {Journal of Chemical Physics},
pages = {1--22},
title = {A universal method for analyzing copolymer growth},
url = {http://dx.doi.org/10.1063/5.0133489},
volume = {158},
year = {2023}
}
TY - JOUR
AB - Polymers consisting of more than one type of monomer, known as copolymers,are vital to both living and synthetic systems. Copolymerisation has beenstudied theoretically in a number of contexts, often by considering a Markovprocess in which monomers are added or removed from the growing tip of a longcopolymer. To date, the analysis of the most general models of this class hasnecessitated simulation. We present a general method for analysing suchprocesses without resorting to simulation. Our method can be applied to modelswith an arbitrary network of sub-steps prior to addition or removal of amonomer, including non-equilibrium kinetic proofreading cycles. Moreover, theapproach allows for a dependency of addition and removal reactions on theneighbouring site in the copolymer, and thermodynamically self-consistentmodels in which all steps are assumed to be microscopically reversible. Usingour approach, thermodynamic quantities such as chemical work; kineticquantities such as time taken to grow; and statistical quantities such as thedistribution of monomer types in the growing copolymer can be derived eitheranalytically or numerically directly from the model definition.
AU - Qureshi,BJ
AU - Juritz,J
AU - Poulton,JM
AU - Beersing-Vasquez,A
AU - Ouldridge,TE
DO - 10.1063/5.0133489
EP - 22
PY - 2023///
SN - 0021-9606
SP - 1
TI - A universal method for analyzing copolymer growth
T2 - Journal of Chemical Physics
UR - http://dx.doi.org/10.1063/5.0133489
UR - http://arxiv.org/abs/2211.02498v2
UR - https://aip.scitation.org/doi/10.1063/5.0133489
UR - http://hdl.handle.net/10044/1/103245
VL - 158
ER -
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