Citation

BibTex format

@article{Davies:2019:10.1016/j.jcf.2019.06.011,
author = {Davies, JC and Drevinek, P and Elborn, JS and Kerem, E and Lee, T and European, CF Society ECFS Strategic Planning Task Force on Speeding up access to new 4 drugs for CF and Amaral, MD and de, Boeck K and Davies, JC and Drevinek, P and Elborn, JS and Kerem, E and Lee, T},
doi = {10.1016/j.jcf.2019.06.011},
journal = {Journal of Cystic Fibrosis},
pages = {677--684},
title = {Speeding up access to new drugs for CF: Considerations for clinical trial design and delivery},
url = {http://dx.doi.org/10.1016/j.jcf.2019.06.011},
volume = {18},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The last decade has witnessed developments in the CF drug pipeline which are both exciting and unprecedented, bringing with them previously unconsidered challenges. The Task Force group was brought together to consider these challenges and possible strategies to address them. Over the last 18months, we have discussed internally and gathered views from a broad range of individuals representing patient organisations, clinical and research teams, the pharmaceutical industry and regulatory agencies. In this and the accompanying article, we discuss two main areas of focus: i) optimising trial design and delivery for speed and efficiency; ii) drug development for patients with rare CFTR mutations. We propose some strategies to tackle the challenges ahead and highlight areas where further thought is needed. We see this as the start of a process rather than the end and hope herewith to engage the wider community in seeking solutions to improved treatments for all patients with CF.
AU  - Davies,JC
AU  - Drevinek,P
AU  - Elborn,JS
AU  - Kerem,E
AU  - Lee,T
AU  - European,CF Society ECFS Strategic Planning Task Force on Speeding up access to new 4 drugs for CF
AU  - Amaral,MD
AU  - de,Boeck K
AU  - Davies,JC
AU  - Drevinek,P
AU  - Elborn,JS
AU  - Kerem,E
AU  - Lee,T
DO  - 10.1016/j.jcf.2019.06.011
EP  - 684
PY  - 2019///
SN  - 1569-1993
SP  - 677
TI  - Speeding up access to new drugs for CF: Considerations for clinical trial design and delivery
T2  - Journal of Cystic Fibrosis
UR  - http://dx.doi.org/10.1016/j.jcf.2019.06.011
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31303382
UR  - https://www.sciencedirect.com/science/article/pii/S156919931930815X?via%3Dihub
UR  - http://hdl.handle.net/10044/1/71918
VL  - 18
ER  -
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