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• Journal article
  Prior E, Santhakumaran S, Gale C, Philipps LH, Modi N, Hyde MJet al., 2012,

  Breastfeeding after cesarean delivery: a systematic review and meta-analysis of world literature

  , AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol: 95, Pages: 1113-1135, ISSN: 0002-9165
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  • Citations: 331
• Journal article
  Gale C, Santhakumaran S, Nagarajan S, Statnikov Y, Modi Net al., 2012,

  Impact of managed clinical networks on NHS specialist neonatal services in England: population based study

  , British Medical Journal, Vol: 344, ISSN: 1468-5833

  Objective To assess the impact of reorganisation of neonatal specialist care services in England after a UK Department of Health report in 2003.Design A population-wide observational comparison of outcomes over two epochs, before and after the establishment of managed clinical neonatal networks.Setting Epoch one: 294 maternity and neonatal units in England, Wales, and Northern Ireland, 1 September 1998 to 31 August 2000, as reported by the Confidential Enquiry into Stillbirths and Sudden Deaths in Infancy Project 27/28. Epoch two: 146 neonatal units in England contributing data to the National Neonatal Research Database at the Neonatal Data Analysis Unit, 1 January 2009 to 31 December 2010.Participants Babies born at a gestational age of 27+0-28+6 (weeks+days): 3522 live births in epoch one; 2919 babies admitted to a neonatal unit within 28 days of birth in epoch two.Intervention The national reorganisation of neonatal services into managed clinical networks.Main outcome measures The proportion of babies born at hospitals providing the highest volume of neonatal specialist care (≥2000 neonatal intensive care days annually), having an acute transfer (within the first 24 hours after birth) and/or a late transfer (between 24 hours and 28 days after birth) to another hospital, assessed by change in distribution of transfer category (“none,” “acute,” “late”), and babies from multiple births separated by transfer. For acute transfers in epoch two, the level of specialist neonatal care provided at the destination hospital (British Association of Perinatal Medicine criteria).Results After reorganisation, there were increases in the proportions of babies born at 27-28 weeks’ gestation in hospitals providing the highest volume of neonatal specialist care (18% (631/3495) v 49% (1325/2724); odds ratio 4.30, 95% confidence interval 3.83 to 4.82; P<0.001) and in acute and late postnatal transfers (7% (235) v 12% (360) and 18% (579)

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• Journal article
  Gale C, Hay A, Philipp C, Khan R, Santhakumaran S, Ratnavel Net al., 2012,

  In-utero transfer is too difficult: Results from a prospective study

  , EARLY HUMAN DEVELOPMENT, Vol: 88, Pages: 147-150, ISSN: 0378-3782
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  • Citations: 22
• Journal article
  Gale C, Logan KM, Santhakumaran S, Parkinson JRC, Hyde MJ, Modi Net al., 2012,

  Effect of breastfeeding compared with formula feeding on infant body composition: a systematic review and meta-analysis

  , AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol: 95, Pages: 656-669, ISSN: 0002-9165
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  • Citations: 179
• Journal article
  Hyde MJ, Mostyn A, Modi N, Kemp PRet al., 2012,

  The health implications of birth by Caesarean section

  , BIOLOGICAL REVIEWS, Vol: 87, Pages: 229-243, ISSN: 1464-7931
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  • Citations: 141
• Journal article
  Thomas EL, Parkinson JR, Hyde MJ, Yap IKS, Holmes E, Dore CJ, Bell JD, Modi Net al., 2011,

  Aberrant Adiposity and Ectopic Lipid Deposition Characterize the Adult Phenotype of the Preterm Infant

  , PEDIATRIC RESEARCH, Vol: 70, Pages: 507-512, ISSN: 0031-3998
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  • Citations: 84
• Journal article
  Wong H, Huertas-Ceballos A, Cowan FM, Modi Net al., 2011,

  COMPARISON OF TWO PARENT-COMPLETED QUESTIONNAIRES FOR THE IDENTIFICATION OF CHILDREN AT RISK FOR AUTISM SPECTRUM DISORDER IN THE PRETERM POPULATION

  , PEDIATRIC RESEARCH, Vol: 70, Pages: 361-361, ISSN: 0031-3998
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• Journal article
  Modi N, 2011,

  'Turning the Tide': increasing and strengthening child health research

  , ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 96, ISSN: 0003-9888
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• Journal article
  Modi N, Murgasova D, Ruager-Martin R, Thomas EL, Hyde MJ, Gale C, Santhakumaran S, Doré CJ, Alavi A, Bell JDet al., 2011,

  The influence of maternal body mass index on infant adiposity and hepatic lipid content.

  , Pediatr Res, Vol: 70, Pages: 287-291

  Maternal overweight and obesity are associated with adverse offspring outcome in later life. The causal biological effectors are uncertain. Postulating that initiating events may be alterations to infant body composition established in utero, we tested the hypothesis that neonatal adipose tissue (AT) content and distribution and liver lipid are influenced by maternal BMI. We studied 105 healthy mother-neonate pairs. We assessed infant AT compartments by whole body MR imaging and intrahepatocellular lipid content by H MR spectroscopy. Maternal BMI ranged from 16.7 to 36.0. With each unit increase in maternal BMI, having adjusted for infant sex and weight, there was an increase in infant total (8 mL; 95% CI, 0.09-14.0; p = 0.03), abdominal (2 mL; 95% CI, 0.7-4.0; p = 0.005), and nonabdominal (5 mL; 95% CI, 0.09-11.0; p = 0.054) AT, and having adjusted for infant sex and postnatal age, an increase of 8.6% (95% CI, 1.1-16.8; p = 0.03) in intrahepatocellular lipid. Infant abdominal AT and liver lipid increase with increasing maternal BMI across the normal range. These effects may be the initiating determinants of a life-long trajectory leading to adverse metabolic health.

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• Journal article
  Modi N, Murgasova D, Ruager-Martin R, Thomas EL, Hyde MJ, Gale C, Santhakumaran S, Dore CJ, Alavi A, Bell JDet al., 2011,

  The Influence of Maternal Body Mass Index on Infant Adiposity and Hepatic Lipid Content

  , PEDIATRIC RESEARCH, Vol: 70, Pages: 287-291, ISSN: 0031-3998
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  • Citations: 121

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