In this section
@article{Conti-Ramsden:2024,
author = {Conti-Ramsden, F and Fleminger, J and Lanoue, J and Chappell, L and Battersby, C},
journal = {British journal of obstetrics and gynaecology},
title = {The contribution of hypertensive disorders of pregnancy to late preterm and term admissions to neonatal units in the UK 2012-2020 and opportunities to avoid admission: a population-based study using the National Neonatal Research Database},
year = {2024}
}
TY - JOUR
AB - Objective: To quantify maternal hypertensive disorder of pregnancy (HDP) prevalence in late preterm and term infants admitted to neonatal units (NNU) and assess opportunities to avoid admissions.Design: A retrospective population-based study using the National Neonatal Research Database.Setting: England and Wales. Population: Infants born ≥ 34 weeks’ gestation admitted to NNU between 2012 and 2020. Methods: Outcomes in HDP infants are compared to non-HDP infants using regression models. Main outcomes measures: HDP, primary reason for admission, clinical diagnoses and resource use.Results: 16,059/136,220 (11.8%) of late preterm (34+0-36+6 weeks’ gestation) and 14,885/284,646 (5.2%) of term (≥ 37 weeks’ gestation) admitted infants were exposed to maternal HDP. The most common primary reasons for HDP infant admission were respiratory disease (28.3%), prematurity (22.7%) and hypoglycaemia (16.4%). HDP infants were more likely to be admitted with primary hypoglycaemia than non-HDP infants (OR: 2.1, 95% CI 2.0-2.2, p-value < 0.0001). 64.5% of HDP infants received IV dextrose. 35.7% received mechanical or non-invasive ventilation. 8260/30,944 (26.7%) of HDP infants received intervention for hypoglycaemia alone (IV dextrose) with no other major intervention (respiratory support, parenteral nutrition, central line, arterial line or blood transfusion). Conclusions: The burden of maternal HDP on late preterm and term admissions to NNU is high with hypoglycaemia and respiratory disease being the main drivers for admission. Over one in four were admitted solely for management of hypoglycaemia. Further research should determine whether maternal antihypertensive agent choice or postnatal pathways may reduce NNU admission.Funding: Medical Research Council (MR/V006835/1).
AU - Conti-Ramsden,F
AU - Fleminger,J
AU - Lanoue,J
AU - Chappell,L
AU - Battersby,C
PY - 2024///
SN - 0306-5456
TI - The contribution of hypertensive disorders of pregnancy to late preterm and term admissions to neonatal units in the UK 2012-2020 and opportunities to avoid admission: a population-based study using the National Neonatal Research Database
T2 - British journal of obstetrics and gynaecology
ER -
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