Representation of three different secretion systems:

Type II Secretion System- T2SS
Type III Secretion System- T3SS
Type IV Secretion System- T4SS

art in science Representation of three different secretion systems

 

 

 

 

 

 

 

 

 

 

 

My name is E. coli, I am versatile bacterium that over the years I evolved many mechanisms to infect my hosts. I have a refined and well-orchestrated mechanism of infection comprising a repertoire of chaperones, translocators, accessory proteins and effectors.

Evolution has favored me to create a conduit to infect my hosts, thrive and survive.

This secretion system is my signature and is playing havoc in the scientific world which is constantly trying to elucidate its assembly process and main virulence factors. 

One has been trying to equate a panacea, but I am a rather mysterious puzzle.

The issues I was causing came to the fore when my fellow scientists discovered that other bacteria that belong to the class of Gammaproteobacteria shared many virulence factors with me.

Although the quest to achieve the fulfilled elucidation of pathogenesis that myself and my relatives cause seems sometimes inaccessible, I would like to provide you with some enlightenment; as Albert Szent-Gyorgyi once said: “Discovery is seeing what everybody else has seen and thinking what nobody else has thought”.

 

Submission by Chloe Seddon, Nanki Singh, and Renata de Vasconcelos

 

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