BibTex format
@article{Pickles:2024:10.1186/s12916-024-03670-y,
author = {Pickles, M and Mountain, E and Bhattacharjee, P and Kioko, J and Musimbi, J and Musyoki, H and Gichangi, P and Stannah, J and Maheu-Giroux, M and Becker, M and Boily, M-C},
doi = {10.1186/s12916-024-03670-y},
journal = {BMC Medicine},
title = {Exploratory analysis of the potential impact of violence on HIV among female sex workers in Mombasa, Kenya: a mathematical modelling study},
url = {http://dx.doi.org/10.1186/s12916-024-03670-y},
volume = {22},
year = {2024}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - BackgroundUnderstanding the frequency of violence experienced by female sex workers (FSWs) and how violence contributes to HIV transmission can help improve HIV programs.MethodsUsing recent recommendations for modelling structural factors and associated causal pathways, we developed a HIV transmission dynamic model for FSWs and their clients in Mombasa, Kenya, mechanistically representing three types of violence (sexual violence, SV; physical violence, PV; police assault and arrest, PAA). Each type of violence affects HIV transmission through key mediators (condom non-use, HIV testing). We parameterized the model using data from a cross-sectional study of FSWs aged 15–24 recruited from a systematic geographical mapping sampling frame in Mombasa, Kenya (Cheuk E et al., Frontiers in Reproductive Health 2(7), 2020). Using this model, calibrated (and cross-validated) to HIV epidemiological and violence outcomes, we estimated the incidence of violence episodes, the contribution of violence to the HIV epidemic measured by the transmission population-attributable fraction, and the potential impact of possible violence interventions.ResultsThe median estimated incidence of PAA in 2023 among FSWs who had not previously experienced that type of violence was 0.20 (95% credible interval: 0.17–0.22) per person-year (ppy), about double the incidence of SV and PV (0.10 (0.09–0.11), 0.11 (0.09–0.12), respectively). The incidence of violence was higher among FSWs who had previously experienced violence: the incidence of recurrent PV was 2.65 (1.82–3.37) ppy, while the incidence of recurrent SV and PAA were 1.26 (0.80–1.67) and 1.37 (0.94–1.74 ppy, respectively. In this setting, we estimated that a median of 35.3% (3.4–55.8%) infections in FSWs and clients combined over the next 10 years may be due to all types of violence (and mediators), mainly through reduced condom use in FSWs who have ever experienced SV (34.6% (2.4–55.5%)).
AU - Pickles,M
AU - Mountain,E
AU - Bhattacharjee,P
AU - Kioko,J
AU - Musimbi,J
AU - Musyoki,H
AU - Gichangi,P
AU - Stannah,J
AU - Maheu-Giroux,M
AU - Becker,M
AU - Boily,M-C
DO - 10.1186/s12916-024-03670-y
PY - 2024///
SN - 1741-7015
TI - Exploratory analysis of the potential impact of violence on HIV among female sex workers in Mombasa, Kenya: a mathematical modelling study
T2 - BMC Medicine
UR - http://dx.doi.org/10.1186/s12916-024-03670-y
UR - http://hdl.handle.net/10044/1/115355
VL - 22
ER -