BibTex format
@article{Allegretti:2021:10.1007/s42000-020-00265-z,
author = {Allegretti, JR and Kassam, Z and Hurtado, J and Marchesi, JR and Mullish, BH and Chiang, A and Thompson, CC and Cummings, BP},
doi = {10.1007/s42000-020-00265-z},
journal = {Hormones},
pages = {209--211},
title = {Impact of fecal microbiota transplantation with capsules on the prevention of metabolic syndrome among patients with obesity},
url = {http://dx.doi.org/10.1007/s42000-020-00265-z},
volume = {20},
year = {2021}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - BackgroundFecal microbiota transplantation (FMT) has been studied for the treatment of metabolic syndrome with varying success. However, the possibility of utilizing FMT to prevent metabolic syndrome is to date unknown.MethodsSecondary analysis of a previously published double-blind, randomized, placebo-controlled pilot trial of FMT in obese metabolically healthy patients was conducted. Post-prandial glucose and insulin levels were measured (NCT02741518).ResultsA total of 22 patients were enrolled, 11 in each arm. There were no baseline differences in the area under the curve (AUC) of glucose or insulin in the FMT group compared to placebo. There was a significant change in glucose AUC at week 12 compared to baseline, and in the insulin AUC at week 6 compared to baseline in the FMT group vs. placebo (change in glucose AUC (mg/dl × 60 min): 579 vs 1978, p = 0.03) (change in insulin AUC (μU/ml × 60 min): 137 vs 2728, p = 0.01).ConclusionsThese data suggest that FMT may have a potential role in preventing the development of metabolic syndrome in patients with obesity.
AU - Allegretti,JR
AU - Kassam,Z
AU - Hurtado,J
AU - Marchesi,JR
AU - Mullish,BH
AU - Chiang,A
AU - Thompson,CC
AU - Cummings,BP
DO - 10.1007/s42000-020-00265-z
EP - 211
PY - 2021///
SN - 1109-3099
SP - 209
TI - Impact of fecal microbiota transplantation with capsules on the prevention of metabolic syndrome among patients with obesity
T2 - Hormones
UR - http://dx.doi.org/10.1007/s42000-020-00265-z
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606403100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR - https://link.springer.com/article/10.1007/s42000-020-00265-z
UR - http://hdl.handle.net/10044/1/112940
VL - 20
ER -