Real world evidence
The iCARE environment holds enormous linked-datasets and by leveraging real-world data, iCARE generates real-world evidence to support the effectiveness and safety of healthcare interventions in actual clinical practice. iCARE has successfully linked patient data with the Imperial Health Knowledge Bank, this will facilitate clinical trial feasibility studies, and access to samples through integration with clinical datasets as study recruitment increases.
Examples
Increasing clinical trial
The use of electronic health records (EHRs) can support the conduct of randomised clinical trials (RCTs) in conditions closer to usual clinical practice. This project will expand consultation with patients and citizens on the acceptable use of their healthcare records for clinical trials within a safe and secure data environment and deploy clinical trial technologies for the design, recruitment, and conduct of studies embedded within digital primary and secondary care clinical records.
Follow-up of interventions
The project aims to use linked healthcare data and additional regional/national data sources to supplement clinical trial data to provide evidence of effectiveness in interventions where good data are lacking. The goal is to understand health and digital inequalities, unintended consequences, and the holistic impact of healthcare interventions by taking a population approach. One exemplar project will evaluate the impact of a digital intervention for a mental health condition on adverse events and improved outcomes for a patient group in the community.
Contact us
For general enquiries email: imperial.dcs@nhs.net
For data access enquiries email: imperial.dataaccessrequest@nhs.net
iCARE social media
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