Our collaborators
Lung diseases account for approximately 10% of all childhood hospitalisations. Lung infections including viral and bacterial and pneumonia account for more than half of admissions while acute asthma makes up at least 20%. One in eleven UK children currently suffers from asthma.
The Respiratory Medicine theme is translational, ranging from pre-clinical, experimental models, to interventional clinical trials of novel medicines. The overall vision is to improve respiratory health for children and young people of all ages and minimise any detrimental long-term impact on adult lung health.
Key interests include mechanisms driving severe asthma and preschool wheezing, lung infections, cystic fibrosis, and Primary Ciliary Dyskinesia, with unique diagnostics including a world-leading bronchoscopic research programme.
The theme has integral links with expertise in basic immunology, systems biology and modelling, bioengineering, bioinformatics, lung physiology and detailed clinical phenotyping. We have close collaborations with colleagues in the Allergy, Primary Care and Acute Care themes.
Education and training are at the heart of our work. We have the highest number of national clinical grid paediatric respiratory trainees of any UK centre and we have at least 3 clinical fellows undertaking postgraduate degrees at any one time. We lead the airways disease modules of the Allergy MSc and have significant contribution to the undergraduate intercalated Respiratory BSc.
Our research and education is fully inclusive of the whole multidisciplinary team, including allied health professionals, clinicians, clinical academics and basic scientists.
Key research areas and theme leadership
Key research areas
- Mechanisms driving asthma and preschool wheezing and novel therapeutics for disease management and prevention
- Novel drug therapies for cystic fibrosis
- Lung physiology
- Novel diagnostic techniques and non-invasive biomarkers of airways diseases
- Lung infections: viral, bacterial, fungal, microbiome
- Airway immunology and remodelling
- Clinical trials
Theme lead
Professor Sejal Saglani
Professor of Paediatric Respiratory Medicine / Director, Centre for Paediatrics and Child Health
Sejal Saglani leads the Paediatric Severe Asthma Group within the Section of Inflammation, Repair and Development and is Honorary Consultant in Paediatric Respiratory Medicine, Royal Brompton Hospital.
She is the Director of the Centre for Paediatrics and Child Health.
Theme members
Professor Andrew Bush
Professor Andrew Bush
Professor of Paediatric Respirology
Dr Adam Byrne
Dr Adam Byrne
Lecturer in Chronic Lung Disease
Dr Siobhán Carr
Dr Siobhán Carr
Consultant in paediatric respiratory medicine
Dr Hanna Creese
Dr Hanna Creese
Research Associate
Professor Jane Davies
Professor Jane Davies
Professor of Paediatric Respirology & Experimental Medicine
Dr Louise Fleming
Dr Louise Fleming
Clinical Senior Lecturer
Dr James Harker
Dr James Harker
Senior Lecturer in Respiratory Science
Professor Claire Hogg
Professor Claire Hogg
Paediatric respiratory consultant
Dr Anthony Laverty
Dr Anthony Laverty
Non-Clinical SPHR Lecturer
Professor Clare Lloyd
Professor Clare Lloyd
Vice-Dean (Institutional Affairs); Faculty of Medicine
Dr Rishi Pabary
Dr Rishi Pabary
Consultant in paediatric respiratory medicine; Honorary senior clinical lecturer
Andreas Perikleous
Andreas Perikleous
Research Postgraduate
Dr Franz Puttur
Dr Franz Puttur
Research Associate
Dr Mark Rosenthal
Dr Mark Rosenthal
Consultant in paediatric respiratory medicine
Professor Sejal Saglani
Professor Sejal Saglani
Professor of Paediatric Respiratory Medicine
Professor Sonia Saxena
Professor Sonia Saxena
Professor of Primary Care
Dr Samatha Sonnappa
Dr Samatha Sonnappa
Consultant in paediatric respiratory medicine