Theme 2: Learning from heart disease patients

Molecular and Genetic Determinants of Adverse Remodelling

Theme 2 aims to identify the environmental, genetic and cellular drivers of how the heart adapts during the transition from health to disease. The program brings together a diverse team of scientists and clinicians working across scales to identify treatable mechanisms of cardiac remodelling. This work bridges population-level discovery science, based on genomics and imaging, with multi-omic analysis of human cells and tissues. 

Theme leads

Co-investigators

Ed Tate

Ed Tate

Fu Siong Ng

Fu Siong Ng

James Ware

James Ware

Julia Gorelik

Julia Gorelik

Manuel Mayr

Manuel Mayr

Key investigators

Andreia Bernardo

Andreia Bernardo

Rasheda Chowdhury

Rasheda Chowdhury

Upasana (Paz) Tayal

Upasana (Paz) Tayal

General enquiries


BHF Centre of Research Excellence
ICTEM Building
Hammersmith Campus
Du Cane Road
London W12 0NN

BHF Centre Manager
Mrs Jaya Rajamanie
j.rajamanie@imperial.ac.uk

+44 (0)20 7594 8062

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@BHFCoREImperial

Faculty of MedicineNational Heart and Lung InstituteVascular Science Network