Theme 2: Learning from heart disease patients
Molecular and Genetic Determinants of Adverse Remodelling
Theme 2 aims to identify the environmental, genetic and cellular drivers of how the heart adapts during the transition from health to disease. The program brings together a diverse team of scientists and clinicians working across scales to identify treatable mechanisms of cardiac remodelling. This work bridges population-level discovery science, based on genomics and imaging, with multi-omic analysis of human cells and tissues.
Theme leads
Declan O'Regan
Declan O'Regan
Clinical
Michela Noseda
Michela Noseda
Translational
Co-investigators
Ed Tate
Ed Tate
Fu Siong Ng
Fu Siong Ng
James Ware
James Ware
Julia Gorelik
Julia Gorelik
Manuel Mayr
Manuel Mayr
Key investigators
Andreia Bernardo
Andreia Bernardo
Rasheda Chowdhury
Rasheda Chowdhury
Upasana (Paz) Tayal
Upasana (Paz) Tayal
General enquiries
BHF Centre of Research Excellence
ICTEM Building
Hammersmith Campus
Du Cane Road
London W12 0NN
BHF Centre Manager
Mrs Jaya Rajamanie
j.rajamanie@imperial.ac.uk
+44 (0)20 7594 8062
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@BHFCoREImperial