About us

Funding

The Glycosciences Laboratory has been supported by research project and programme grants from the MRC, Wellcome Trust, BBSRC, EPSRC, and the NCI Alliance of Glycobiologists the US National Institute of Health.

Current and recent funding:

• Wellcome Trust Biomedical Resource Grant (Nov 2019- Oct 2023) to support the Carbohydrate Microarray Facility. “Carbohydrate Microarray Facility for the New Era of Glycomics” Press release
  
• The Imperial College-March of Dimes European Prematurity Research Centre grant (2018-2023) (Coordinator: Phillip Bennett)
  
• NIH Commons fund GlyGen Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Structural, Analytical, and Interaction” (2017-2022)
• MRC Research Grant “Characterizing the stress-associated glycan ligand for collectin-11 on renal tubular epithelial cells” (2018-2021) (PI: Steven Sacks, King’s College London)   
• BBSRC/EPSRC/Innovate UK: Industrial Biotechnology Catalyst Early Stage Translation grant “Chemo-enzymatic Production of Specialty Glycans” (2015-2021) (PI: Dr Bruno Linclau, Southampton University)

Equipment

Robotic arrayers for generating microarrays of lipid-linked glycan probes, polysaccharides and glycoproteins

• GeSiM - Nano-Plotter 

Fluorescent microarray scanners used to quantify fluorescent signals on microarrays

• GenePix 4300A Scanners with Automated Slide Loader

Mass Spectrometers used for carbohydrate composition and sequence analyses

• ESI-MS instrument with a Q-TOF configuration (Waters SYNAPT G2-S)
• MALDI mass spectrometer with an Ion-Trap/TOF configuration (Shimadzu Axima Resonance)
• MALDI mass spectrometer with a linear TOF configuration (Shimadzu Axima Assurance)
• GC-MS system (FinniganTrace MS)

Access at MRC Biomedical NMR Center  (now part of the Francis Crick Institute) to

• 700 MHz Bruker cryoprobe NMR spectrometers