In this section
@article{Herrero:2018:10.1109/TBME.2017.2787423,
author = {Herrero, P and Rawson, TM and Philip, A and Moore, LSP and Holmes, AH and Georgiou, P},
doi = {10.1109/TBME.2017.2787423},
journal = {IEEE Transactions on Biomedical Engineering},
pages = {2231--2236},
title = {Closed-loop control for precision antimicrobial delivery: an In silico proof-of-concept},
url = {http://dx.doi.org/10.1109/TBME.2017.2787423},
volume = {65},
year = {2018}
}
TY - JOUR
AB - IEEE Objective: Inappropriate dosing of patients with antibiotics is a driver of antimicrobial resistance, toxicity, and poor outcomes of therapy. In this paper, we investigate, in silico, the hypothesis that the use of a closed-loop control system could improve the attainment of pharmacokinetic-pharmacodynamic targets for antimicrobial therapy, where wide variations in target attainment have been reported. This includes patients in critical care, patients with renal disease and patients with obesity.
AU - Herrero,P
AU - Rawson,TM
AU - Philip,A
AU - Moore,LSP
AU - Holmes,AH
AU - Georgiou,P
DO - 10.1109/TBME.2017.2787423
EP - 2236
PY - 2018///
SN - 0018-9294
SP - 2231
TI - Closed-loop control for precision antimicrobial delivery: an In silico proof-of-concept
T2 - IEEE Transactions on Biomedical Engineering
UR - http://dx.doi.org/10.1109/TBME.2017.2787423
UR - http://hdl.handle.net/10044/1/56020
VL - 65
ER -
