In this section
@article{Hellewell:2021:10.1098/rstb.2019.0817,
author = {Hellewell, J and Sherrard-Smith, E and Ogoma, S and Churcher, TS},
doi = {10.1098/rstb.2019.0817},
journal = {Philosophical Transactions of the Royal Society B: Biological Sciences},
pages = {1--9},
title = {Assessing the impact of low-technology emanators alongside long-lasting insecticidal nets to control malaria},
url = {http://dx.doi.org/10.1098/rstb.2019.0817},
volume = {376},
year = {2021}
}
TY - JOUR
AB - Malaria control in sub-Saharan Africa relies on the widespread use of long-lasting insecticidal nets (LLINs) or the indoor residual spraying of insecticide. Disease transmission may be maintained even when these indoor interventions are universally used as some mosquitoes will bite in the early morning and evening when people are outside. As countries seek to eliminate malaria, they can target outdoor biting using new vector control tools such as spatial repellent emanators, which emit airborne insecticide to form a protective area around the user. Field data are used to incorporate a low-technology emanator into a mathematical model of malaria transmission to predict its public health impact across a range of scenarios. Targeting outdoor biting by repeatedly distributing emanators alongside LLINs increases the chance of elimination, but the additional benefit depends on the level of anthropophagy in the local mosquito population, emanator effectiveness and the pre-intervention proportion of mosquitoes biting outdoors. High proportions of pyrethroid-resistant mosquitoes diminish LLIN impact because of reduced mosquito mortality. When mosquitoes are highly anthropophagic, this reduced mortality leads to more outdoor biting and a reduced additional benefit of emanators, even if emanators are assumed to retain their effectiveness in the presence of pyrethroid resistance. Different target product profiles are examined, which show the extra epidemiological benefits of spatial repellents that induce mosquito mortality.
AU - Hellewell,J
AU - Sherrard-Smith,E
AU - Ogoma,S
AU - Churcher,TS
DO - 10.1098/rstb.2019.0817
EP - 9
PY - 2021///
SN - 0962-8436
SP - 1
TI - Assessing the impact of low-technology emanators alongside long-lasting insecticidal nets to control malaria
T2 - Philosophical Transactions of the Royal Society B: Biological Sciences
UR - http://dx.doi.org/10.1098/rstb.2019.0817
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000603646400013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - https://royalsocietypublishing.org/doi/10.1098/rstb.2019.0817
UR - http://hdl.handle.net/10044/1/85797
VL - 376
ER -