Members use a wide range of techniques (gene tagging, silencing, microarrays, RNA/ChIP-seq, -omics technologies) and imaging approaches (high-throughput microscopy to in vivo whole animal and single cell resolution), in addition to in silico structural modelling and mathematical modelling of gene families, molecular pathways, and complex cellular systems. The groups in this theme focus on the cellular and molecular mechanisms which regulate development, maintenance, repair and regeneration of tissues. We use a variety of experimental models, including mouse, zebrafish, C. elegans, Drosophila, Arabidopsis, Blumeria graminis, and a range of protozoan and metazoan pathogens.
Studies on individual cells/organisms are complemented by population studies in an effort to understand the evolutionary drivers of gene selection. Strong links with groups in Physics, Chemistry, Mathematics and Engineering support the development of novel, interdisciplinary approaches that take advantage of cutting-edge technological advances to address challenging biological questions.
Institutes, centres and initiatives
This Research Theme is associated to the following institutes, centres and initiatives:
- Antimicrobial Research Collaborative
- Centre for Advanced Therapeutics
- Department of Immunology and Inflammation
- Hic-Vac
- Institute of Infection
- Malaria Network
- Physics of Life Network
- Stem Cell Regenerative Medicine Network
- Vascular Science Network
- Wound Healing and Regeneration Network
Academic Staff in this area
Dr Michalis Barkoulas
Dr Michalis Barkoulas
Reader in Molecular Genetics
Professor Jake Baum
Professor Jake Baum
Visiting Professor
Dr Tolga Bozkurt
Dr Tolga Bozkurt
Reader in Molecular Plant-Microbe Interactions
Professor Hugh J M Brady
Professor Hugh J M Brady
Professor of Immunology
Dr Laurence Bugeon
Dr Laurence Bugeon
Research Fellow
Dr Matthew A Child
Dr Matthew A Child
Senior Research Fellow
Dr Ste Cook
Dr Ste Cook
Principal Teaching Fellow
Professor Andrea Crisanti
Professor Andrea Crisanti
Professor of Molecular Parasitology
Dr Tiago Cunha Luis
Dr Tiago Cunha Luis
Sir Henry Dale Fellow
Professor Maggie Dallman OBE
Professor Maggie Dallman OBE
Associate Provost (Societal Engagement)
Professor Daniel M Davis
Professor Daniel M Davis
Head of Department of Life Sciences, Chair in Immunology
Professor Marc S Dionne
Professor Marc S Dionne
Professor of Innate Immunity
Professor Robert G Endres
Professor Robert G Endres
Professor of Systems Biology
Dr Kleoniki Gounaris
Dr Kleoniki Gounaris
Senior Lecturer
Dr Anita C Hall
Dr Anita C Hall
Senior Teaching Fellow
Dr Dave Hartley
Dr Dave Hartley
Senior Teaching Fellow
Professor Cristina Lo Celso
Professor Cristina Lo Celso
Co-Director Centre for Haematology & Prof Stem Cell Biology
Dr Catherine Mansfield
Dr Catherine Mansfield
Senior Strategic Teaching Fellow
Dr Atieme Joseph Ogbolosingha
Dr Atieme Joseph Ogbolosingha
Teaching Fellow
Dr Ruben Perez-Carrasco
Dr Ruben Perez-Carrasco
Senior Lecturer in Theoretical Systems Biology
Emeritus Professor Murray Selkirk
Emeritus Professor Murray Selkirk
Emeritus Professor in Molecular Parasitology
Dr Giovanni Sena
Dr Giovanni Sena
Senior Lecturer
Dr Jie Song
Dr Jie Song
Research Fellow (The Royal Society)
Dr Tony D Southall
Dr Tony D Southall
Reader in Molecular Genetics
Dr Marco Trizzino
Dr Marco Trizzino
Senior Lecturer in Developmental Genomics
Professor Colin G N Turnbull
Professor Colin G N Turnbull
Professor of Plant Sciences
Dr Dina Vlachou
Dr Dina Vlachou
Senior Research Fellow
Postgraduate research
Interested in studying a PhD at the Department of Life Sciences? Find out more about postgraduate research opportunties.