Researchers at Imperial are working to identify how host genetics affect responses to viral or bacterial infections.
Researchers in this field include:
- Professor Anthony Gordon: Developing host RNA-based diagnostics for sepsis
- Professor Mike Levin: DIAMONDs project: Developing host RNA-based diagnostics
- Dr Vanessa Sancho-Shimizu: Understanding the genetic basis of life-threatening infections
- Dr Anand Shah: Understanding host susceptibility to Aspergillus fumigatus
- Professor Armstrong-James: Clinical host-pathogen interactions, focussing on the interplay between pathogen genomics and diversity and host systems immunology in the context of underlying clinical disease states
- Professor Peter Openshaw: Immune response to pathogens
- Dr Ivana Pennisi: Developing host RNA-based point of care diagnostics
- Professor James Seddon: Using host omics for diagnosis of TB in children and prediction of future TB disease progression, understanding host genetic susceptibility to TB meningitis
- Dr Avinash Shenoy: Inflammasome and caspases in host-defence against bacterial pathogens
- Professor Marc Dionne: How does host genetics change the antimicrobial effects of immune defences?
- Dr Matthew Child: Understanding interactions of eukaryotic pathogens with their chosen host-cell using drug-like small molecules and functional genomics
Links
DIAMONDS: An EU Horizon2020 project to develop a molecular test for the rapid diagnosis of serious infectious and inflammatory diseases using personalised gene signatures.
