Digestive diseases researchers at Imperial are exploring:
- Liver failure: All forms of liver failure are accompanied by increased susceptibility to infection arising from immune paresis. Using both ex-vivo and animal model approaches enables the mechanism of the immune defects to be identified and then potentially to be addressed as novel therapeutic approaches.
- Inflammatory bowel disease (IBD): The prevalence of both ulcerative colitis and Crohn’s Disease are increasing globally. Despite a plethora of immune targeted monoclonal inhibitors which improve symptoms and reduce disease severity, there are no cures for IBD. Understanding the immunopathology of this condition, particularly by focussing on the interaction of the mucosal innate immune system with the gut microbiome may identify key mechanisms appropriate for therapeutic intervention.
Members
Dr Elsa Angelini
Dr Elsa Angelini
Senior Data Scientist
Professor David Carling
Professor David Carling
Professor of Biochemistry
Professor Waljit Dhillo
Professor Waljit Dhillo
Professor of Endocrinology & Metabolism
Professor Robert Glen
Professor Robert Glen
Chair in Computational Medicine
Dr Mathieu Latreille
Dr Mathieu Latreille
Honorary Senior Lecturer
Dr Victoria Male
Dr Victoria Male
Lecturer in Reproductive Immunology
Dr Nick Powell
Dr Nick Powell
Clinical Reader in Gastroenterology
Professor Mark Thursz
Professor Mark Thursz
Professor of Hepatology. Head of Department
Dr Evangelos Triantafyllou
Dr Evangelos Triantafyllou
Advanced Research Fellow