BibTex format
@article{Weld:2024:10.1007/s00701-024-06179-8,
author = {Weld, A and Dixon, L and Anichini, G and Patel, N and Nimer, A and Dyck, M and O'Neill, K and Lim, A and Giannarou, S and Camp, S},
doi = {10.1007/s00701-024-06179-8},
journal = {Acta Neurochirurgica: the European journal of neurosurgery},
title = {Challenges with segmenting intraoperative ultrasound for brain tumours},
url = {http://dx.doi.org/10.1007/s00701-024-06179-8},
volume = {166},
year = {2024}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Objective - Addressing the challenges that come with identifying and delineating brain tumours in intraoperative ultrasound. Our goal is to both qualitatively and quantitatively assess the interobserver variation, amongst experienced neuro-oncological intraoperative ultrasound users (neurosurgeons and neuroradiologists), in detecting and segmenting brain tumours on ultrasound. We then propose that, due to the inherent challenges of this task, annotation by localisation of the entire tumour mass with a bounding box could serve as an ancillary solution to segmentation for clinical training, encompassing margin uncertainty and the curation of large datasets. Methods - 30 ultrasound images of brain lesions in 30 patients were annotated by 4 annotators - 1 neuroradiologist and 3 neurosurgeons. The annotation variation of the 3 neurosurgeons was first measured, and then the annotations of each neurosurgeon were individually compared to the neuroradiologist's, which served as a reference standard as their segmentations were further refined by cross-reference to the preoperative magnetic resonance imaging (MRI). The following statistical metrics were used: Intersection Over Union (IoU), Sørensen-Dice Similarity Coefficient (DSC) and Hausdorff Distance (HD). These annotations were then converted into bounding boxes for the same evaluation. Results - There was a moderate level of interobserver variance between the neurosurgeons [ I o U : 0.789 , D S C : 0.876 , H D : 103.227 ] and a larger level of variance when compared against the MRI-informed reference standard annotations by the neuroradiologist, mean across annotators [ I o U : 0.723 , D S C : 0.813 , H D : 115.675 ] . After converting the segments to bounding boxes, all metrics improve, most significantly, the interquartile range drops by [ I o U : 37 % , D S C : 41 % , H D : 54 % ] . Conclusion - This study highlights the current challenges with detecting and defining tumour boundaries in neuro-oncologi
AU - Weld,A
AU - Dixon,L
AU - Anichini,G
AU - Patel,N
AU - Nimer,A
AU - Dyck,M
AU - O'Neill,K
AU - Lim,A
AU - Giannarou,S
AU - Camp,S
DO - 10.1007/s00701-024-06179-8
PY - 2024///
SN - 0001-6268
TI - Challenges with segmenting intraoperative ultrasound for brain tumours
T2 - Acta Neurochirurgica: the European journal of neurosurgery
UR - http://dx.doi.org/10.1007/s00701-024-06179-8
UR - https://www.ncbi.nlm.nih.gov/pubmed/39090435
UR - https://link.springer.com/article/10.1007/s00701-024-06179-8
UR - http://hdl.handle.net/10044/1/113810
VL - 166
ER -