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@inproceedings{Kim:2019:10.1117/12.2507961,
author = {Kim, JA and Wales, DJ and Thompson, AJ and Yang, G-Z},
doi = {10.1117/12.2507961},
publisher = {SPIE},
title = {Towards development of fibre-optic surface enhanced Raman spectroscopy probes using 2-photon polymerisation for rapid detection of bacteria},
url = {http://dx.doi.org/10.1117/12.2507961},
year = {2019}
}
TY - CPAPER
AB - In this study, a variety of direct laser written surface-enhanced Raman spectroscopy (SERS) micro-structures, designed for bacteria detection, are presented. Various SERS micro-structures were designed to achieve both a high density of plasmonic hot spots and a strong probability of interaction between the hot spots and the target bacterial cells. Twophoton polymerization was used for initial fabrication of the polymeric skeletons of the SERS micro-structures, which were then coated with a 50 nm-thick gold layer via e-beam evaporation. The micro-structures were fabricated on glass coverslips and were assessed using a confocal Raman microscope. To this end, Rhodamine 6G was used as an analyte under 785 nm laser illumination. The optimal SERS micro-structures showed approximately 7×103 enhancement in Raman signal (analytical enhancement factor, AEF) at a wavenumber of 600 cm-1. Real-time detection of E. coli in solution was demonstrated using the fabricated SERS platform with low laser powers and a short acquisition time (785 nm, 5 mW, 50 ms).
AU - Kim,JA
AU - Wales,DJ
AU - Thompson,AJ
AU - Yang,G-Z
DO - 10.1117/12.2507961
PB - SPIE
PY - 2019///
SN - 0277-786X
TI - Towards development of fibre-optic surface enhanced Raman spectroscopy probes using 2-photon polymerisation for rapid detection of bacteria
UR - http://dx.doi.org/10.1117/12.2507961
UR - http://hdl.handle.net/10044/1/70994
ER -
