People

Professor Ed Tate
Director

Professor Matthew Fuchter
Co-Director

Professor Iain McNeish
Co-Director

Dr Pedro Ballester
Cancer, bacterial disease, antibiotic-resistance

Dr Sylvain Ladame
Diagnostics / Chemical biology / Biosensors

Dr Guy-Bart Stan
Synthetic biology / Biological systems modelling / Antibiotic resistance

Dr Reiko J. Tanaka
Computational modelling / Machine learning analysis

Professor Alan Armstrong
Covalent fragments

Dr Anna Barnard
Protein-protein interactions / Infectious disease / Chemical tools

Dr James Bull
Fragment synthesis / Bioisostere design / Late stage functionalisation

Dr Rob Davies
Drug delivery platforms

Dr Marco Di Antonio
DNA targeting / Epigenetic Drugs

Dr Jarvist Moore Frost
Graph neural networks; shape similarity; transition state analogues

Dr Yuval Elani
Smart drug delivery / Artificial cells / Tissue models

Dr Lindsay Evans
Antibiotic resistance / Antibiotic drug discovery

Professor Matthew Fuchter
Medicinal chemistry / Chemical biology / Photopharmacology

Professor David Klug
Closed loop lead development / Personalised therapy / Tissue imaging / Novel structural biology

Dr Philip Miller
PET Imaging / Radiotracer development / Radiolabelling chemistry

Dr Ben Schumann
Posttranslational modifications / Glycosylation / Cell-cell interactions

Professor Alan Spivey
Synthesis / Medicinal chemistry / Imaging agents

Professor Ed Tate
Drug target deconvolution and target validation / Chemical biology / Medicinal chemistry

Professor Ramon Vilar
Medicinal chemistry / Chemical Biology / Molecular Imaging

Dr Louise Walport
Chemical biology / Peptide chemistry / Biophysics

Professor Keith Willison
Control of cell growth and cell cycle processes / Actin and microtubule inhibitors

Professor David Carling
AMPK in metabolic diseases and cancer

Professor Jesus Gil
Liver cancer, fibrosis, NASH

Professor Christian Speck
Cryo-EM / DNA replication / Chromatin

Dr Geoff Baldwin
Drug delivery, Protein nanocages, Blood-brain barrier

Dr Konstantinos Beis
Membrane protein transporters / Histamine GPCRs / Antibiotic resistance

Professor Bernadette Byrne
Membrane transport mechanisms / Discovery of novel therapies to treat fungal disease

Dr Matthew Child
In vivo phenotypic screening / Antimicrobial discovery and evolution \ Chemical probe development

Dr Michael Delves
Malaria / Microscopy / High throughput screening

Professor Kurt Drickamer
Improved adjuvants for vaccine development / Inhibitors of autoimmunity / Adjuvant design

Dr David Mann
Covalent drugs / Oncology / Assay development

Professor Steve Matthews
Bacterial infections / Apicomplexan parasite disease / Apoptosis / Drug resistance

Dr Masahiro Ono
T cells/ Immunotherapy

Professor Micheal Sternberg
Logic-based drug discovery / Protein modelling / Protein-protein interactions

Dr Joseph Boyle
Gene regulation in inflammation and atherosclerosis

Dr Vania Braga
Cell-cell Adhesion Signalling

Dr Silvia A. Ferreira
Cell-matrix interactions, hydrogels and nanomedicine targeted delivery

Professor Kazuhiro Ito
Bacerial diseases/inflammatory diseases/ageing/drug delivery

Professor Tony Magee
Inhibitors of posttranslational processing of secreted signalling molecules, e.g. Hedgehogs, Wnts

Dr Michela Noseda
Cardiac Molecular Pathology

Professor Micheal Schneider
Cardiovascular disease / Cell death / Kinases

Dr Sonya Abraham
Inflammatory disease skin, gut, joint, brain

Dr Holger Auner
Protein degradation and metabolism in multiple myeloma / Haematopoietic malignancies

Professor Sir Steve Bloom
Obesity / Peptide drug delivery / Receptor pharmacology

Dr Andrew Edwards
Novel antibacterial therapeutics

Professor Guido Franzoso
Molecular biology/ Transcriptional regulation/ Cell signalling

Professor Gary Frost
Nutrient based small molecules / GPCRs

Professor Anastasios Karadimitris
Transcription factors and chromatin binding proteins in multiple myeloma

Professor Paul Langford
Tuberculosis / Antimicrobial peptides / Antibiotics

Dr Sandra Newton
Infectious diseases / Drug discovery / Anti-microbial peptides (AMP)

Dr Brian Robertson
Antimicrobial peptides / Tuberculosis / Imaging

Dr Alejandra Tomas
Chemical biology / Receptor signaling / Biosensors

Professor Simak Ali
Molecular Endocrine Oncology

Professor Charlotte Bevan
Nuclear receptors / Hormone-dependent cancers / Therapeutic delivery

Professor Robert Brown
Epigenetics / Drug resistance / Cancer biomarkers

Professor Naomi Chayen
Protein crystals / Crystallography

Professor Charles Coombes
CDK7 Nuclear Receptos Transcription

Dr Aylin Hanyaloglu
G protein-coupled receptors

Professor Iain McNeish
Co-Director

Dr Vassele Vassileva
Theragnostics, Oncology, Radioimmunotherapy

Professor Mauricio Barahona
Mathematical modelling of structures and pathways / Data-driven omics analysis / Machine learning

Dr Paul Bilokon
Paroxysmal atrial fibrillation/Covid-19/molecular modelling/PPIs/(photo)pharmacology

Professor Paul French
High content analysis/ Multidimensional fluorescence imaging