BibTex format
@article{Faiz:2011:10.1111/j.1463-1318.2010.02290.x,
author = {Faiz, O and Haji, A and Bottle, A and Clark, SK and Darzi, AW and Aylin, P},
doi = {10.1111/j.1463-1318.2010.02290.x},
journal = {Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland},
pages = {779--785},
title = {Elective colonic surgery for cancer in the elderly: an investigation into postoperative mortality in English NHS hospitals between 1996 and 2007},
url = {http://dx.doi.org/10.1111/j.1463-1318.2010.02290.x},
volume = {13},
year = {2011}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - BACKGROUND: This study was primarily aimed to quantify perioperative mortality risk in elderly patients undergoing elective colonic resectional surgery. In addition, the safety of minimally invasive colonic surgery in this patient group was evaluated. METHODS: All patients aged > 75 undergoing elective colonic resection for colorectal malignancy between 1996 and 2007 in English NHS hospitals were included from the Hospital Episode Statistics (HES) dataset. RESULTS: Between the study dates, 28,746 patients > 75 years underwent elective colonic resection. The national annual number of colonic excisions carried out amongst elderly patients increased from 2188 patients in 1996/7 to 3240 patients in 2006/7. Following adjustment for gender, comorbidity and surgical approach, advancing age was an independent predictor for 30-day mortality (OR 2.47 for patients aged 85-89 vs 75-79, P < 0.001). Use of laparoscopy was a significant predictor of reduced perioperative mortality (OR 0.56, P = 0.003) once adjusted for advancing age, gender and comorbidity. Comparison of 30-day and 1-year postoperative mortality following elective colonic resection in patients aged 90 revealed a large excess of patients dying outside of the immediate perioperative period (10.1% and 26.2% for proximal cancers, respectively; 12.9% and 36.1% for distal colonic resections, respectively). CONCLUSIONS: Advancing age is an independent risk factor for postoperative death in elderly patients undergoing elective colonic resection for cancer. The risk of death in the elderly is extremely high and surgical decision-making should incorporate the mortality risk that occurs outside the immediate perioperative period. In this national series, patients selected for a laparoscopic procedure were at lower risk of perioperative death than those undergoing the conventional approach.
AU - Faiz,O
AU - Haji,A
AU - Bottle,A
AU - Clark,SK
AU - Darzi,AW
AU - Aylin,P
DO - 10.1111/j.1463-1318.2010.02290.x
EP - 785
PY - 2011///
SN - 1463-1318
SP - 779
TI - Elective colonic surgery for cancer in the elderly: an investigation into postoperative mortality in English NHS hospitals between 1996 and 2007
T2 - Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
UR - http://dx.doi.org/10.1111/j.1463-1318.2010.02290.x
UR - http://www.ncbi.nlm.nih.gov/pubmed/20412094
VL - 13
ER -
