Contact
Group lead
Prof Eric Aboagye
+44 (0)20 3313 3759
eric.aboagye@imperial.ac.uk
Related themes
Disease areas
What we do
We are involved in the discovery, development and application of imaging methods, mainly positron emission tomography (PET), magnetic resonance imaging (MRI), and ultrasound (US) for clinical studies of cancer biology, physiology and pharmacology, as well as experimental studies of tumour models. Our aim is to develop methods that will make a significant impact on patient care in the short to medium term; and in the long term train the next generation of imaging scientists.
Why it is important
Our research aims to detect cancer and cancer phenotypes quicker and in a more sensitive way, as well as stratify patients more effectively to therapy, particularly in the context of drug development. The very rapid changes in molecular targets and pathways associated with anti-cancer treatment, evident in days rather than weeks, means that we can in the future detect response to therapy much earlier than current clinical standards of radiological shrinkage. Understanding disease biology in different tumour types will ultimately permit personalised medicine to be delivered to patients in the form of ‘theranostics’ (detect-and-treat).
How it can benefit patients
Our work helps in diagnosis, prognosis and treatment of cancer.
Summary of current research
- Imaging of therapy response - development and application of caspase-3 and nucleoside salvage markers
- Imaging of cell surface receptors and theranostic (detect & treat) applications - EGFR, SSTR2, HER2, CXCR4
- Imaging cancer metabolism - fatty acid oxidation, glycogenesis, choline and nucleoside metabolism
- Novel radiochemistry & radiotracer discovery and translational research
- Radiomics and machine learning for cancer detection and prognosis.
- Cancer pharmacology - choline kinase and HDAC6
Connections
- Cancer Research UK Imperial Centre
- Development of novel imaging agents including first in man trials
- Cancer drug development - experimental medicine (Phase I/II)
- Imaging & molecular biomarker studies
When we have funding for PhD studentships, we advertise them through central channels such as Find a PhD. Information is also available on the Surgery and Cancer study page. If no studentships are currently advertised, please get in touch with the group lead with proposed project titles to discuss further.
Current PhD students:
- Jin Hui Teh
- Barbara Dworakowska
- Michael Komodromos
- Ben Hunter
- Sumeet Hindocha
- Hardeep Kalsi
- Stanislav Piletsky (Joint with Alan Spivey, Chemistry)
- Camarie Welgemoed
- Ala Amgheib
- Jamie Beaumont
- Zixuan Yang
- Marc Boubnovski
- Kristofer Lindon-Reid
- Sumran Kukran
Our researchers
Our researchers
Professor Eric O Aboagye
Professor Eric O Aboagye
Professor (Director)
Professor Andrea Rockall
Professor Andrea Rockall
Clinical Chair in Radiology (Co-director)
Benjamin Hunter
Benjamin Hunter
Honorary Clinical Research Fellow
Mohammed Al Sad
Mohammed Al Sad
NCITA Imaging Repository Developer
Olga Fadeeva Da Costa
Olga Fadeeva Da Costa
Honorary Clinical Research Fellow
Dr Ning Wang
Dr Ning Wang
Research Associate
Mr Chris Barnes
Mr Chris Barnes
Research Scientist
Dr Bill Crum
Dr Bill Crum
Data Science Engineer (Lead)
Marianna Inglese
Marianna Inglese
Research Associate
Mrs Joyce Daniels
Mrs Joyce Daniels
https://www.imperial.ac.uk/people/j.daniels
Dr Laura M Kenny
Dr Laura M Kenny
Clinical Senior Lecturer in Medical Oncology
Miss Laura McLeavy
Miss Laura McLeavy
Clinical Trial Coordinator
Dr Haonan Lu
Dr Haonan Lu
Data Science Engineer
Dr Mitchell Chen
Dr Mitchell Chen
Clinical Lecturer
Dr Rohini Sharma
Dr Rohini Sharma
Reader in Clinical Pharmacology & Medical Oncology
Dr Sumeet Hindocha
Dr Sumeet Hindocha
Clinical Research Fellow
Dr Preetha Aravind
Dr Preetha Aravind
Clinical Research Fellow
Tim Hoogenboom
Tim Hoogenboom
Research Sonographer
Xingfeng Li
Xingfeng Li
Research Associate
Cancer Imaging Research Group