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@article{Valentini:2016:10.1074/jbc.R115.711507,
author = {Valentini, M and Filloux, A},
doi = {10.1074/jbc.R115.711507},
journal = {Journal of Biological Chemistry},
pages = {12547--12555},
title = {Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria},
url = {http://dx.doi.org/10.1074/jbc.R115.711507},
volume = {291},
year = {2016}
}
TY - JOUR
AB - The cyclic-di-GMP (c-di-GMP) second messenger represents a signaling system that regulates many bacterial behaviors and is of key importance for driving the lifestyle switch between motile loner cells and biofilm formers. This review provides an up-to-date compendium of c-di-GMP pathways connected to biofilm formation, biofilm-associated motilities and other functionalities in the ubiquitous and opportunistic human pathogen Pseudomonas aeruginosa. This bacterium is frequently adopted as model organism to study bacterial biofilm formation. Importantly, its versatility and adaptation capabilities are linked with a broad range of complex regulatory networks, including a large set of genes involved in c-di-GMP biosynthesis, degradation and transmission.
AU - Valentini,M
AU - Filloux,A
DO - 10.1074/jbc.R115.711507
EP - 12555
PY - 2016///
SN - 1083-351X
SP - 12547
TI - Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria
T2 - Journal of Biological Chemistry
UR - http://dx.doi.org/10.1074/jbc.R115.711507
UR - http://hdl.handle.net/10044/1/32711
VL - 291
ER -
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