Citation

BibTex format

@article{Mathavan:2014:10.1038/NCHEMBIO.1499,
author = {Mathavan, I and Zirah, S and Mehmood, S and Choudhury, HG and Goulard, C and Li, Y and Robinson, CV and Rebuffat, S and Beis, K},
doi = {10.1038/NCHEMBIO.1499},
journal = {Nature Chemical Biology},
pages = {340--342},
title = {Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides},
url = {http://dx.doi.org/10.1038/NCHEMBIO.1499},
volume = {10},
year = {2014}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The lasso peptide microcin J25 is known to hijack the siderophore receptor FhuA for initiating internalization. Here, we provide what is to our knowledge the first structural evidence on the recognition mechanism, and our biochemical data show that another closely related lasso peptide cannot interact with FhuA. Our work provides an explanation on the narrow activity spectrum of lasso peptides and opens the path to the development of new antibacterials.
AU - Mathavan,I
AU - Zirah,S
AU - Mehmood,S
AU - Choudhury,HG
AU - Goulard,C
AU - Li,Y
AU - Robinson,CV
AU - Rebuffat,S
AU - Beis,K
DO - 10.1038/NCHEMBIO.1499
EP - 342
PY - 2014///
SN - 1552-4450
SP - 340
TI - Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides
T2 - Nature Chemical Biology
UR - http://dx.doi.org/10.1038/NCHEMBIO.1499
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000334672700006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - https://www.nature.com/articles/nchembio.1499
UR - http://hdl.handle.net/10044/1/27441
VL - 10
ER -

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