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@article{Fisher:2016:10.1007/978-1-4939-2854-5_15,
author = {Fisher, RA and Cheverton, AM and Helaine, S},
doi = {10.1007/978-1-4939-2854-5_15},
journal = {Methods in Molecular Biology},
pages = {177--187},
title = {Analysis of Macrophage-Induced Salmonella Persisters.},
url = {http://dx.doi.org/10.1007/978-1-4939-2854-5_15},
volume = {1333},
year = {2016}
}
TY - JOUR
AB - A small subpopulation of non-replicating, multidrug-tolerant bacteria is present within clonal populations of many bacterial species. Known as persisters, these bacteria are probably the cause of relapsing infections such as typhoid fever. Formation of non-growing Salmonella persisters is stimulated by macrophage phagocytosis. This chapter outlines methods to identify and study persisters resulting from interactions between bacterial pathogens and their hosts. We use their antibiotic tolerance for isolation and enumeration and developed a method to study the heterogeneity of growth within clonal populations through single-cell analysis.
AU - Fisher,RA
AU - Cheverton,AM
AU - Helaine,S
DO - 10.1007/978-1-4939-2854-5_15
EP - 187
PY - 2016///
SN - 1940-6029
SP - 177
TI - Analysis of Macrophage-Induced Salmonella Persisters.
T2 - Methods in Molecular Biology
UR - http://dx.doi.org/10.1007/978-1-4939-2854-5_15
VL - 1333
ER -
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