In this section
@article{Geraldes:2015:10.1007/s10237-015-0740-7,
author = {Geraldes, DM and Modenese, L and Phillips, ATM},
doi = {10.1007/s10237-015-0740-7},
journal = {Biomechanics and Modeling in Mechanobiology},
pages = {1029--1042},
title = {Consideration of multiple load cases is critical in modelling orthotropic bone adaptation in the femur},
url = {http://dx.doi.org/10.1007/s10237-015-0740-7},
volume = {15},
year = {2015}
}
TY - JOUR
AB - Functional adaptation of the femur has beeninvestigated in several studies by embedding bone remodellingalgorithms in finite element (FE) models, with simpli-fications often made to the representation of bone’s materialsymmetry and mechanical environment. An orthotropicstrain-driven adaptation algorithm is proposed in order topredict the femur’s volumetric material property distributionand directionality of its internal structures within a continuum.The algorithm was applied to a FE model of the femur,with muscles, ligaments and joints included explicitly. Multipleload cases representing distinct frames of two activitiesof daily living (walking and stair climbing) were considered.It is hypothesised that low shear moduli occur in areasof bone that are simply loaded and high shear moduli inareas subjected to complex loading conditions. In addition,it is investigated whether material properties of differentfemoral regions are stimulated by different activities. The loading and boundary conditions were considered to providea physiological mechanical environment. The resultingvolumetric material property distribution and directionalitiesagreed with ex vivo imaging data for the whole femur.Regions where non-orthogonal trabecular crossing has beendocumented coincided with higher values of predicted shearmoduli. The topological influence of the different activitiesmodelled was analysed. The influence of stair climbing onthe properties of the femoral neck region is highlighted. It isrecommended that multiple load cases should be consideredwhen modelling bone adaptation. The orthotropic model ofthe complete femur is released with this study.
AU - Geraldes,DM
AU - Modenese,L
AU - Phillips,ATM
DO - 10.1007/s10237-015-0740-7
EP - 1042
PY - 2015///
SN - 1617-7959
SP - 1029
TI - Consideration of multiple load cases is critical in modelling orthotropic bone adaptation in the femur
T2 - Biomechanics and Modeling in Mechanobiology
UR - http://dx.doi.org/10.1007/s10237-015-0740-7
UR - http://hdl.handle.net/10044/1/27709
VL - 15
ER -
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