In this section
@article{Zhao:2018:10.1302/2046-3758.78.BJR-2018-0025.R1,
author = {Zhao, S and Arnold, M and Ma, S and Abel, R and Cobb, J and Hansen, U and Boughton, OR},
doi = {10.1302/2046-3758.78.BJR-2018-0025.R1},
journal = {Bone and Joint Research},
pages = {524--538},
title = {Standardising compression testing for measuring the stiffness of human bone: a systematic review},
url = {http://dx.doi.org/10.1302/2046-3758.78.BJR-2018-0025.R1},
volume = {7},
year = {2018}
}
TY - JOUR
AB - Objectives: The ability to determine human bone stiffness is of clinical relevance in many fields, including bone quality assessment and orthopaedic prosthesis design. Stiffness can be measured using compression testing; an experimental technique commonly used to test bone specimens in vitro. This systematic review aims to determine how best to perform compression testing of human bone. Methods: A keyword search of all English language articles up until December 2017 of compression testing of bone was undertaken in Medline, Embase, PubMed and Scopus databases. Studies using bulk tissue, animal tissue, whole bone or testing techniques other than compression testing were excluded. Results: 4712 abstracts were retrieved with a total of 177 papers included in the analysis. 20 studies directly analysed the compression testing technique to improve the accuracy of the testing technique. Several influencing factors should be considered when testing bone samples in compression. These include the method of data analysis, specimen storage, specimen preparation, testing configuration and loading protocol. Conclusions: Compression testing is a widely used technique for measuring the stiffness of bone but there is a great deal of inter-study variation in experimental techniques across the literature. Based on best evidence from the literature, suggestions for bone compression testing are made in this review, though further studies are needed to help establish standardised bone testing techniques to increase the comparability and reliability of bone stiffness studies.
AU - Zhao,S
AU - Arnold,M
AU - Ma,S
AU - Abel,R
AU - Cobb,J
AU - Hansen,U
AU - Boughton,OR
DO - 10.1302/2046-3758.78.BJR-2018-0025.R1
EP - 538
PY - 2018///
SN - 2046-3758
SP - 524
TI - Standardising compression testing for measuring the stiffness of human bone: a systematic review
T2 - Bone and Joint Research
UR - http://dx.doi.org/10.1302/2046-3758.78.BJR-2018-0025.R1
UR - http://hdl.handle.net/10044/1/60456
VL - 7
ER -
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