Isobel Steer

Real-time monitoring of DNA interactions using Whispering Gallery Mode (WGM) Resonators

My project is focused on using Whispering Gallery Mode (WGM) resonators for monitoring the interactions of DNA sequences such as G quadruplexes in real time. The goal is to develop the WGM sensor as a tool for DNA study and drug development.

Mini-Bio:

• MRes/PhD, Bioengineering, Imperial College London, (currently); Supervisors: Dr Joshua Edel and Dr Sylvain Ladame.
• MRes, Biomedical Research, Imperial College London (2013-2014); Supervisors: Dr Sylvain Ladame, Dr Danny O’Hare, Dr James Flanagan, Professor Robert Brown.
• BA (Hons) Biological Sciences, University of Oxford (2010-2013).

Publications

Panich, S., Haj Sleiman, M., Steer, I., Ladame, S., & Edel, J. B. (2016). Real-Time Monitoring of Ligand Binding to G-Quadruplex and Duplex DNA by Whispering Gallery Mode Sensing. ACS Sensors, 1(9), 1097-1102.